C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/18 (2006.01) C12N 5/12 (2006.01) C12N 15/62 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2149883
2149883 9412521 PCTABS00032 This invention provides an isolated nucleic acid molecule encoding a retinoblastoma-associated protein, and isolated proteins having transcriptional factor E2F biological activity and RB-binding activity. This invention also provides vectors comprising an isolated nucleic acid molecule encoding a retinoblastoma-associated protein, mammalian cells comprising such vectors, antibodies directed to the retinoblastoma-associated protein and hybridoma lines producing monoclonal antibodies to such protein. This invention further provides methods for using such antibodies diagnostically and prognostically.
Lee Wen-Hwa
Shan Bei
Gowling Lafleur Henderson Llp
The Board Of Regents Of The University Of Texas System
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