Cellular immunogenicity potentiating composition containing...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/09 (2010.01) C12N 5/071 (2010.01) A61K 31/7028 (2006.01) A61K 35/12 (2006.01) A61K 39/00 (2006.01) A61K 39/39 (2006.01) C07H 15/04 (2006.01) C07H 15/10 (2006.01)

Patent

CA 2304378

A composition for potentiating the immunogenicity of tumor cells or pathogen- infected cells, which contains a compound having the .alpha.-glycosylceramide structure, salts thereof or solvates of both. Tumor cells having the immunogenicity potentiated by the compounds having the .alpha.- glycosylceramide structure are useful in the oncotherapy (cancer vaccine therapy).

On décrit une composition pouvant potentialiser l'immunogénicité de cellules tumorales ou de cellules infectées par un agent pathogène. Cette composition contient un composé présentant la structure glycosylcéramide alpha, des sels ou des solvats dudit composé ou les deux substances à la fois. Les cellules tumorales dont l'immunogénicité a été potentialisée au moyen desdits composés présentant la structure glycosylcéramide alpha s'utilisent efficacement dans l'oncothérapie (thérapie anticancéreuse).

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