Cellular labeling for nuclear magnetic resonance techniques

Details Cellular labeling for nuclear magnetic resonance techniques Cellular labeling for nuclear magnetic resonance techniques

C - Chemistry, Metallurgy

08

L

C08L 71/02 (2006.01) A61K 49/10 (2006.01) C08J 3/02 (2006.01)

Patent

CA 2560544

The disclosure provides, in part, fluorocarbon imaging reagents and formulations for the ex vivo labeling of cells. Labeled cells may be detected in vivo or ex vivo by a nuclear magnetic resonance technique, such as magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS). The disclosure additionally provides methods for using the imaging reagents in a variety of clinical procedures.

L'invention concerne, en partie, des réactifs d'imagerie à fluorocarbones et des formulations pour le marquage ex vivo de cellules. Les cellules marquées peuvent être détectées in vivo ou ex vivo par une technique à résonance magnétique nucléaire, telle que l'imagerie par résonance magnétique (IRM) et la spectroscopie par résonance magnétique. L'invention concerne également des procédés pour utiliser les réactifs d'imagerie dans une pluralité de procédures cliniques.

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