Cellular signaling pathway based assays, reagents and kits

Details Cellular signaling pathway based assays, reagents and kits Cellular signaling pathway based assays, reagents and kits

G - Physics

01

N

G01N 33/53 (2006.01) C07H 21/02 (2006.01) C12M 1/00 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2589413

The present invention is directed to an assay system, PAM (Pathway Assay Matrix) for screening drug to determine whether they are effective for treating or preventing a disease or disorder. This assay system takes into account that many diseases involve complex pathways, and measures the effect of a particular drug on the multiple nodes within the disease pathway of a particular disease or disorder.

Cette invention concerne un système de dosage, appelé PAM (matrice de dosage de voies), servant au criblage de médicaments, en vue de déterminer s'ils sont efficaces pour traiter ou prévenir une maladie ou un trouble. Ce système de dosage prend en compte le fait que de nombreuses maladies impliquent des voies complexes et il mesure l'effet d'un médicament particulier sur les noeuds multiples de la voie d'une maladie ou d'un trouble particuliers.

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