Cellulases, nucleic acids encoding them and methods for...

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/06 (2006.01) A61K 38/43 (2006.01) A62D 3/00 (2007.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 1/20 (2006.01) C12N 9/24 (2006.01) C12N 9/26 (2006.01) C12N 9/42 (2006.01) C12N 15/00 (2006.01) C12P 19/14 (2006.01) C12P 19/18 (2006.01) C12P 19/20 (2006.01) C12P 21/04 (2006.01) D06M 16/00 (2006.01) D21C 1/04 (2006.01)

Patent

CA 2611859

This invention relates to molecular and cellular biology and biochemistry. In one aspect, the invention provides polypeptides having cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or .beta.-glucosidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or .beta.- glucosidase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts.

L'invention se rapporte aux domaines de la biologie moléculaire et cellulaire, et de la biochimie. Un des aspects de l'invention concerne des polypeptides possédant une activité cellulase, p. ex. endoglucanase, cellobiohydrolase, mannanase et/ou ß-glucosidase, des polynucléotides codant pour ces polypeptides, et des procédés de production et d'utilisation de ces polynucleotides et polypeptides. Dans un aspect, l'invention porte sur l'activité cellulase des polypeptides, p. ex. endoglucanase, cellobiohydrolase, mannanase et/ou ß- glucosidase, présentant une activité thermostable et thermotolérante, et sur des polynucléotides codant pour ces enzymes, ainsi que sur la production et l'utilisation de ces polynucléotides et polypeptides. Les polypeptides décrits peuvent être utilisés dans divers contextes pharmaceutiques, agricoles, de transformation de produits alimentaires et d'aliments pour animaux, et industriels.

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