C - Chemistry – Metallurgy – 08 – J
Patent
C - Chemistry, Metallurgy
08
J
18/15, 182/14.1
C08J 9/26 (2006.01) D01D 5/24 (2006.01)
Patent
CA 1153171
ABSTRACT OF THE DISCLOSURE This specification provides an improved cellulose semi- permeable hollow fiber which is melt extruded from a cellulose ester melt spin composition which is sulfolane free and contains only low molecular weight polyols and the melt spun fibers possess substantially improved intrinsic tensile strength during wet processing steps which remove the polyol and hydrolyze the fibers to cellulose; the resulting cellulose fibers are characterized by substantially increased water permeability and improved clearance capabilities for separating low molecular weight impurities from blood such as urea, creatinine and the like. The improved cellulose hollow fiber of this invention is characterized by possessing an intrinsic wet tensile strength of about 2 X 104 to about 11 X 104 grams. intrinsic fiber tensile strength per gram of cellulose polymer, a water permeability or ultrafiltration coefficient KUFR in the range of about 2 to 200 millimeters per hour per square meter per millimeter of mercury pressure across the semi- permeable wall of the fiber, and a urea clearance coefficient KUREA in the range of about 15 X 10-3 to about 45 X 10-3 centimeters per minute at 37°C. These functional character- istics qualify such fibers for use in blood detoxification processes including hemodialysis and hemofiltration. The improved cellulose semipermeable hollow fibers of this invention are made by melt spinning a cellulose ester melt spin composition consisting of about 35% to about 80%, by weight, of a selected cellulose ester, or mixtures thereof, and a polyol, or mixtures thereof, having an average molecular weight in the range of about 106 to about 900.
361632
Chen David T.
Mahoney Robert D.
Cordis Dow Corp.
Gowling Lafleur Henderson Llp
LandOfFree
Cellulose semipermeable hollow fibers and method for making... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cellulose semipermeable hollow fibers and method for making..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cellulose semipermeable hollow fibers and method for making... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-512916