Central nervous system damage

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61P 25/28 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12N 15/12 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) C40B 30/02 (2006.01) C40B 30/04 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 31/7088 (2006.01) C12N 15/11 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2508847

The application provides peptides that interact with the inhibitory domains of the myelin proteins Nogo, TNR and MAG. These may be used in the treatment for CNS damage, and for the development of further treatments. Also provided are methods and materials for immunizing subjects against the inhibitory domains of the myelin proteins, for the treatment for CNS damage.

L'invention a trait à des peptides qui interagissent avec les domaines inhibiteurs des protéines de la myéline Nogo, TNR et MAG. Lesdits peptides peuvent servir à traiter des lésions du système nerveux central, et à mettre au point d'autres traitements. L'invention concerne également des procédés et des matériaux permettant d'immuniser des sujets contre les domaines inhibiteurs des protéines de la myéline, afin de traiter des lésions du système nerveux central.

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