A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 29/00 (2006.01) A61K 38/15 (2006.01) A61L 29/06 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01)
Patent
CA 2181819
The invention relates to central venous polyurethane catheters with a thin hydrophilic coating loaded with an antibiotic of the ramoplanin group or any mixture thereof and their use in preventing catheter related infections. These catheters are useful to prevent bacterial adherence and colonization and, therefore, to lower the risk of vascular infections in catheterized patients. The method of preparing the catheter of the invention consists in incubating polyurethane catheters coated with a hydrophilic film in an aqueous solution of the selected antibiotic.
Cathéters de veine centrale en polyuréthane munis d'un revêtement hydrophile mince chargé d'un antibiotique du groupe ramoplanine ou de tout mélange renfermant celui-ci, et leur utilisation dans la prévention d'infections associées à l'usage d'un cathéter. Ces cathéters sont utilisables dans la prévention de l'adhérence et de la colonisation bactériennes, et permettent, de ce fait, de réduire le risque d'infections vasculaires chez les malades traités au moyen d'un cathéter. Le procédé de préparation de ce cathéter consiste à mettre en incubation dans une solution aqueuse de l'antibiotique choisi les cathéters en polyuréthane munis d'un revêtement hydrophile.
Denaro Maurizio
Goldstein Beth P.
Romano' Gabriella
Williams Rosamund Jean
Biosearch Italia S.p.a.
Smart & Biggar
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