Centrally-acting muscle relaxants

Details Centrally-acting muscle relaxants Centrally-acting muscle relaxants

A - Human Necessities

61

K

167/235

A61K 31/42 (2006.01) C07D 261/12 (2006.01)

Patent

CA 1291041

ABSTRACT Isoxazolin-3-one derivatives represented by the general formula Image (I) [in which, R1 represents a hydrogen atom or a halogen atom; R2 represents a lower alkyl group, an aryl group or a heterocyclic group; or R1 and R2, together with the adjacent carbon atoms, form a hydrocarbon ring; R3 represents a hydrogen atom or a lower alkyl group; R4 represents a lower alkyl group; or R3 and R4 together with the adjacent nitrogen atom, may form an alicyclic amino group]. and their pharmaceutically acceptable acid addition salts are useful as centrally- acting muscle relaxants.

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