Centrifugal method and apparatus for isolating a substance...

Details Centrifugal method and apparatus for isolating a substance... Centrifugal method and apparatus for isolating a substance...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) B01D 21/26 (2006.01) B04B 5/00 (2006.01) B04B 5/04 (2006.01) C07H 1/06 (2006.01) C12M 1/10 (2006.01) C12M 1/26 (2006.01) C12M 3/00 (2006.01) C12N 15/10 (2006.01) C12Q 1/24 (2006.01) G01N 1/40 (2006.01)

Patent

CA 2156860

A centrifugal rotor (1) effects the isolation, in a sequence of steps, of a substance from a mixture of substances dissolved, suspended or dispersed in a sample liquid. Multiple samples are processed simultaneously by means of a plurality of fractionation cells (2), each of which contains a series of interconnected, chambered and vented compartments in which individual steps of the fractionation and isolation procedure take place. The interconnections, chambers and passages of each compartment are sized and angled to prevent predetermined amounts of sample and reagent liquids from overflowing the compartment. Predetermined amounts of the reagent liquids required to contact the sample in individual steps of the isolation process are simultaneously delivered to specific compartments of every cell (2) by means of a dynamic flow distributor (3) which accepts partially aerosolized injections of said reagents pipetted from a dosator (22) while the centrifugal rotor (1) is rotating.

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