Centrosome-associated protein and applications thereof

Details Centrosome-associated protein and applications thereof Centrosome-associated protein and applications thereof

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2511436

The invention relates to a novel centrosome-associated protein, to the polynucleotide coding for the aforementioned protein and to the applications of said protein and polynucleotide. The overexpression of the inventive protein disrupts the mitotic spindle assembly and leads to aberrant and abortive mitoses.

L'invention est relative une nouvelle protéine associée aux centrosomes, au polynucléotide codant pour ladite protéine ainsi qu'aux applications de ladite protéine et dudit polynucléotide. La surexpression de la protéine selon l'invention entraîne des perturbations dans l'organisation du fuseau mitotique et induit des mitoses aberrantes et abortives.

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