Cephalosporin analogs for oral use

Details Cephalosporin analogs for oral use Cephalosporin analogs for oral use

C - Chemistry, Metallurgy

07

D

260/244.2

C07D 498/04 (2006.01) C07D 505/00 (2006.01)

Patent

CA 1214166

ABSTRACT OF THE DISCLOSURE 7.beta.-(2-cyano-aliphatic acylamino)-7.alpha.-methoxy-3-heterocyclic thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acids and salts or pharmacologically acceptable esters generically represented by the following formula are potent antibacterials. and esters are prospective oral drugs: Image (wherein A is a lower alkyl, lower alkenyl or lower alkynyl group; B is a hydrogen atom, salt forming atom, salt forming group or physiologically hydrolyzable ester group; and Het is a heterocyclic group) - 1 -

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