Cephalosporin antibiotic

Details Cephalosporin antibiotic Cephalosporin antibiotic

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/46 (2006.01) A61K 31/54 (2006.01) A61K 31/545 (2006.01) C07D 417/12 (2006.01) C07D 501/00 (2006.01) C07D 501/12 (2006.01) C07D 501/56 (2006.01) C07D 501/60 (2006.01)

Patent

CA 1142919

ABSTRACT (6R,7R)-7- [(Z) -2-(2-Aminothiazol-4-yl)-2-(2- carboxyprop-2-oxyimino)acetamido]-3-(1-pyridiniummethyl)- ceph-3-em-4-carboxylate in the form of its crystalline pentahydrate. This pentahydrate has a well defined crystalline structure and exhibits good stability on storage. The pentahydrate exhibits excellent antibiotic activity, particularly against organisms which are normally difficult to combat with .beta.-lactam antibiotics.

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