Cephalosporin antibiotics

C - Chemistry – Metallurgy – 07 – D

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C07D 501/36 (2006.01) A61K 31/545 (2006.01) C07D 519/00 (2006.01) C07D 519/06 (2006.01)

Patent

CA 1339418

Cephalosporin compounds of Formulas II (see fig. II) where R is hydrogen or a pharmaceutical cation, in which case R1 is not present, or R is hydrogen or a chemical bond when R1 is an acid addition salt anion, and R2 is (a) hydrogen, (b) a duplicate of the formula I compound to form a dimer, (c) an aminocarbonylmethyl, or (d) an -SR3 group where R3 is alkyl, cyclohexyl, phenyl, chloro-substituted phenyl, nitro-substituted phenyl, benzyl or furfuryl, have been found to be valuable as antibiotics for treating warm-blooded animals to combat pathogenic bacterial infections which cause diseases such as the commonly known "shipping fever".

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