Cephalosporin antibiotics

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 501/59 (2006.01) A61K 31/545 (2006.01) A61K 31/695 (2006.01) C07D 463/00 (2006.01) C07D 477/00 (2006.01) C07D 477/20 (2006.01) C07D 498/04 (2006.01) C07D 499/88 (2006.01) C07D 501/00 (2006.01) C07D 503/00 (2006.01) C07D 505/00 (2006.01) C07D 513/04 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2186894

The present invention includes novel(7R)-7-(acylamino)-3-(arylthio)-3-cephem-4-carboxyylic acids or their pharmacologically acceptable salts which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistant to .beta.- lactam antibiotics and are useful as antibacterial agents. The invention also relates to novel intermediates useful for making the novel compounds of the present invention and to novel methods for producing the novel compounds and intermediate compounds.

Nouveaux acides (7R)-7-(acylamino)-3-(arylthio)-3-céphèm-4-carboxyliques, ou leurs sels pharmacologiquement acceptables, présentant une activité antibiotique dirigée contre un grand nombre d'organismes tels que les organismes résistants aux bêta-lactamines et utilisables comme agents antibactériens. On a également prévu de nouveaux intermédiaires servant à fabriquer ces nouveaux composés, ainsi que de nouveaux procédés de production de ces nouveaux composés et composés intermédiaires.

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