Cephalosporin antibiotics

Details Cephalosporin antibiotics Cephalosporin antibiotics

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/22 (2006.01) C07D 277/20 (2006.01)

Patent

CA 1130279

ABSTRACT OF THE DISCLOSURE Cephalosporin antibiotics of general formula Image (I) (wherein Ra and Rb, which may be the same or different, each represent a C1-4 alkyl group or Ra and Rb together with the carbon atom to which they are attached form a C3-7 cyclo- alkylidene group) exhibit broad spectrum antibiotic activity, particularly high activity against members of the Enterobacteriaceae, The invention also includes the non-toxic salts and non-toxic metabolically labile esters of compounds of formula (I), Also described are compositions containing the antibiotics of the invention and processes for the preparation of the antibiotics,

328414

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