Cephalosporin antibiotics

Details Cephalosporin antibiotics Cephalosporin antibiotics

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/36 (2006.01) A61K 31/545 (2006.01) C07D 501/46 (2006.01) C07D 501/56 (2006.01)

Patent

CA 1131216

ABSTRACT OF THE DISCLOSURE Cephalosporin antibiotics of general formula Image (I) (wherein Y ? represents a C-attached 1-C1-4alkyl- pyridinium group) exhibit broad spectrum antibiotic activity with unusually high activity against strains of Pseudomonas organisms as well as high activity against various members of the Enterobacteriaceae. The invention also includes the non-toxic salts and non-toxic meta- bolically labile esters of compounds of formula (I). Also described are compositions containing the antibiotics of the invention and processes for the preparation of the antibiotics.

339970

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