Cephalosporin compounds

Details Cephalosporin compounds Cephalosporin compounds

C - Chemistry, Metallurgy

07

D

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C07D 501/16 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/04 (2006.01) C07D 501/18 (2006.01) C07D 501/36 (2006.01) C07D 501/48 (2006.01) C07D 501/60 (2006.01) C07D 501/44 (2006.01) C07D 501/46 (2006.01)

Patent

CA 1100129

ABSTRACT OF THE DISCLOSURE The present invention relates to a new class of cephalosporin compounds having in the 3-position a 5-oxo-6-hydroxy-4,5-dihydro-1,2,4-triazin-3-ylthiomethyl group and to a process for the preparation thereof character- ized by reacting a 3-acetoxymethylcephalosporin compound with a 3-mercapto-5-oxo-6-hydxoxy-4,5-dihydro-1,2,4-tria- zine. The 3-triazinylthiomethylcephalosporin compounds have excellent broad spectrum gram-positive and gram- negative antibiotic activity. X-4273A

232136

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