Cephalosporin compounds and preparation thereof

C - Chemistry – Metallurgy – 07 – D

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260/104.1

C07D 501/24 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1231940

-56- ABSTRACT A cephalosporin compound of the formula: Image (I) wherein R1 is hydrogen or lower alkyl; R2 is acetoxy or (1-methyl-1H-tetrazol-5-yl)thio, and R3 is carboxy; or R2 is a group of the formula: Image , R3 is -COO- and Y is hydroge, hydroxymethyl or carbamoyl; and n is an integer of 2 or 3, or a pharmaceutically acceptable salt thereof and processes for their preparation are disclosed. Said cephalosporin compound is useful as an antimicrobial agent.

433824

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