Cephalosporin compounds and processes for preparing the same

Details Cephalosporin compounds and processes for preparing the same Cephalosporin compounds and processes for preparing the same

C - Chemistry, Metallurgy

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167/187, 260/104

C07D 501/46 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/24 (2006.01) C07D 501/38 (2006.01) C07D 501/44 (2006.01) C07D 501/56 (2006.01)

Patent

CA 1284995

ABSTRACT OF THE DISCLOSURE A cephalosporin compound of the formula: (I) Image wherein R1 is a protected or unprotected amino group; either one of R2 and R3 is a lower alkylthio group, a hydroxy-lower alkylthio group, a formylamino-lower alkylthio group, a carboxy-lower alkylthio group, sulfamoyl group, a lower alkylsulfonyl group, sulfo group, amino group, formylamino group, carbamoylamino group, a lower alkanoylamino group, an N,N-di(lower alkyl)amino group, an N-formyl-N-lower alkylamino group, a lower alkylamino group, an N-(lower alkylsulfonyl)-amino group, a hydroxy-lower alkanoylamino group, a halogen atom, a lower alkoxy groups carboxy group, a formylamino-lower alkyl group, an amino-lower alkyl group, a lower alkylthio-lower alkyl group or a lower alkyl group; and the other one of R2 and R3 is hydrogen atom, carbamoyl group, amino group, formylamino group, a hydroxy-lower alkyl group or a lower alkyl group; or R2 and R3 are located at the 2- and 3-position of the pyridine ring and combined together to form an alkylene group of 3 or 4 carbon atoms; or a salt thereof and processes for preparing the same are disclosed. The cephalosporin compound (I) is useful as an antimicrobial agent.

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