Cephalosporin derivatives

Details Cephalosporin derivatives Cephalosporin derivatives

C - Chemistry, Metallurgy

07

D

260/100

C07D 501/18 (2006.01) C07C 205/35 (2006.01) C07D 233/28 (2006.01) C07D 233/68 (2006.01) C07D 233/90 (2006.01) C07D 257/04 (2006.01)

Patent

CA 1175805

ABSTRACT OF THE DISCLOSURE A compound of the formula I:- Image I in which R1 is any C-3 substituent from antibacterially-active cephalosporins; R2 is any C-4 substituent from antibacterially- active cephalosporins; R3 is H, hydroxy, amino, 1-6C alkyl, 1-6C alkanoyl, 1-6C alkoxy, 1-6C alkanoylamino or 1-6C alkylamino, phenyl(1-6C)-alkyl or phenyl, each optionally substituted by methoxy; Image is of the formula II or III:- Image Image II III in which R4, R5, R6, R7, R8 and R9 are radicals described in the specification; and the salts thereof. Manufacturing processes, pharmaceutical compositions and a method of treating a bacterial infection are also disclosed.

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