Cephalosporin derivatives

Details Cephalosporin derivatives Cephalosporin derivatives

C - Chemistry, Metallurgy

07

D

C07D 501/48 (2006.01) A61K 31/545 (2006.01) A61K 31/675 (2006.01) A61K 31/695 (2006.01) A61K 31/70 (2006.01) C07D 213/70 (2006.01) C07D 501/00 (2006.01) C07F 7/10 (2006.01) C07F 9/547 (2006.01) C07H 5/06 (2006.01)

Patent

CA 2169400

Novel cephem derivatives represented by the general formula Image in which the Acyl substituent is a group of the formula Image wherein Ar is a lipophilic optionally substituted phenyl, naphthyl, pyridyl or benzthiazolyl group; R1 is selected from certain optionally substituted aliphatic, aromatic, arylaliphatic or sugar moieties and R2 and R3 are each independently hydrogen, alkyl or aminoalkylcarbonylamino are gram-positive antibacterial agents, especially useful in the treatment of infectious diseases caused by methicillin-resistant Staphylococcus aureus (MRSA).

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