Cephalosporin derivatives, a process for their preparation...

C - Chemistry – Metallurgy – 07 – D

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260/104.1

C07D 501/34 (2006.01) C07D 277/20 (2006.01)

Patent

CA 1172248

ABSTRACT: "CEPHALOSPORIN DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM" Compounds of formula (I): Image (I) wherein: R1 represents a hydrogen atom or a methyl group; and R2 represents a C1-C5 alkyl or alkoxy group; and pharmaceutically acceptable acid addition salts thereof are valuable antibiotics suitable for oral adminstration. They may be prepared by reacting a compound of formula (II): Image (II) (wherein X represents a halogen atom and R1 and R2 are as defined above) with thiourea.

387049

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