Cephalosporin hydroxamic acids

Details Cephalosporin hydroxamic acids Cephalosporin hydroxamic acids

C - Chemistry, Metallurgy

07

D

260/100, 167/188

C07D 498/04 (2006.01) A61K 31/43 (2006.01) C07D 501/16 (2006.01) C07D 505/00 (2006.01)

Patent

CA 1251785

- 1 - SHIONOGI SEIYAKU KABUSHIKI KAISHA CEPHALOSPORIN HYDROXAMIC ACIDS Inventors: Wataru Nagata, Yasuhiro Nishitani and Tsutomiu Aoki. - ABSTRACT - An antibacterial cephalosporin hydroxamic acid derivative represented by the following formula (I), processes for its preparation, compositions containing the same as an active ingredient, and a method for killing bacteria by contacting with said compound. (I) Image (wherein, R is acyl; R1 is hydrogen or methoxy; R2 is alkylene; R3 is an aliphatic group; R4 is hydrogen or amino-protecting group; R5 is hydrogen, light metal atom or carboxy-protecting group; and X is oxygen, sulfur, or sulfinyl).

447498

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