Cephalosporins

Details Cephalosporins Cephalosporins

C - Chemistry, Metallurgy

07

D

167/187, 260/104

C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 257/04 (2006.01) C07D 277/20 (2006.01)

Patent

CA 1308708

NEW CEPHALOSPORINS Abstract of the disclosure . A 7-(2-(2-aminothiazol-4-yl)-2-(syn)-methoxyimino- acetamido)cephalosporin derivative of the formula; Image wherein R3 is hydrogen or a residue of a nucleophilic compound; R2NH is an amino group which may optionally be protected, pharmaceutically acceptable salt or ester thereof, is found to have excellent anti-bacterial activity against a broad spectrum of bacteria inclusive of gram- negative bacteria such as Escherichia coli, Serratia marcescens, Proteus rettgeri,Enterobacter cloacae and Citrobacter freundii. Thus, this compound may be used for an antibacterial agent in therapeutical purposes.

276067

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