C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/104.1
C07D 501/46 (2006.01) A61K 31/545 (2006.01) C07D 417/04 (2006.01) C07D 501/00 (2006.01) C07D 501/04 (2006.01) C07D 501/36 (2006.01) C07D 501/38 (2006.01) C07D 501/44 (2006.01) C07D 501/56 (2006.01)
Patent
CA 1213882
Abstract of the Disclosure Disclosed are novel cephalosporin derivatives of the formula Image I wherein R1 is hydrogen or a conventional amino-protecting group, and R2 is a straight or branched alkyl group containing from 1 to 4 carbon atoms, allyl, 2-butenyl or 3-butenyl, or is a group Image wherein R3 and R4 each are independently hydrogen, methyl or ethyl, or R3 and R4, taken together with the carbon atom to which they are attached, may be a cycloalkylidene ring containing from 3 to 5 carbon atoms, and nontoxic pharmaceutically acceptable salts, physiologically hydrolyzable esters and solvates thereof and processes for their preparation. Said novel cephalosporin derivatives exhibit potent antibacterial activity.
420788
Aburaki Shimpei
Kamachi Hajime
Naito Takayuki
Narita Yukio
Okumura Jun
Bristol-Myers Company
Gowling Lafleur Henderson Llp
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