Cephalosporins

Details Cephalosporins Cephalosporins

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/46 (2006.01) A61K 31/545 (2006.01) C07D 417/04 (2006.01) C07D 501/00 (2006.01) C07D 501/04 (2006.01) C07D 501/36 (2006.01) C07D 501/38 (2006.01) C07D 501/44 (2006.01) C07D 501/56 (2006.01)

Patent

CA 1213882

Abstract of the Disclosure Disclosed are novel cephalosporin derivatives of the formula Image I wherein R1 is hydrogen or a conventional amino-protecting group, and R2 is a straight or branched alkyl group containing from 1 to 4 carbon atoms, allyl, 2-butenyl or 3-butenyl, or is a group Image wherein R3 and R4 each are independently hydrogen, methyl or ethyl, or R3 and R4, taken together with the carbon atom to which they are attached, may be a cycloalkylidene ring containing from 3 to 5 carbon atoms, and nontoxic pharmaceutically acceptable salts, physiologically hydrolyzable esters and solvates thereof and processes for their preparation. Said novel cephalosporin derivatives exhibit potent antibacterial activity.

420788

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