Cephalosporins and homologues, preparations and...

C - Chemistry – Metallurgy – 07 – D

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C07D 501/20 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) A61K 31/545 (2006.01) C07D 463/00 (2006.01) C07D 501/00 (2006.01) C07D 501/18 (2006.01)

Patent

CA 2087967

.beta.-Lactam antibiotics of formula (I) or a salt thereof, wherein R2 is hydrogen, methoxy or formamido; R2 is an acyl group; CO2R3 is a carboxy group or a carboxylate anion, or R3 is a readily removable carboxy protecting group; R4 repres- ents up to four substituents; X is S, SO, SO2, O or CH2; m is 1 or 2; and n is 0, useful in the treatment of bacterial infec- tions in humans and animals.

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