Cephapirin salts with amino acids

Details Cephapirin salts with amino acids Cephapirin salts with amino acids

C - Chemistry, Metallurgy

07

D

260/105.1

C07D 501/34 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/12 (2006.01)

Patent

CA 1133471

ABSTRACT OF THE DISCLOSURE The invention relates to salts of cephapirin with an amino acid selected from the group consisting of L - lysine, L - arginine and acetylcy- steine. Said salts are obtained reacting an aqueous solution of cephapirin with an aqueous solution of an amino acid or its derivative, selected from the group consisting of L - lysine, L - arginine and acetylcysteine. To isolate the salt, the aqueous solution is submitted to lyophilization. The salts of the invention can be injected without causing such as pain as when the sodium salt of cephapirin is injected.

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