Cephem compound, its production and its use for producing...

Details Cephem compound, its production and its use for producing... Cephem compound, its production and its use for producing...

C - Chemistry, Metallurgy

07

D

C07D 501/16 (2006.01) C07D 501/00 (2006.01) C07D 519/00 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2127902

ABSTRACT A 3-[(E)-1-propenyl]cephem compound represented by formula (I): Image (I) wherein R represents hydrogen, a protective group for an amino group, or the group shown by formula (II): Image (II) in which R3 is a protective group for an amino group, R4 is a protective group for a hydroxyl group, and W is -CH= or -N=; R2 represents a protective group for a carboxyl group: and X represents hydrogen or chlorine. The compound is useful as an intermediate for producing cephem antibiotics and is prepared by isomerizing the corresponding 3-[(Z)-1-propenyl]cephem compound in an inert organic solvent in the presence of an aromatic thiol. The compound of formula (I) wherein X is chlorine can be converted into a 3-[(E)-3-ammonio-1- propenyl]cephem derivative through the reaction with a tertiary amine.

Affiliated with

Also associated with

Rating

Cephem compound, its production and its use for producing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cephem compound, its production and its use for producing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cephem compound, its production and its use for producing... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1822102