Cephem compounds

Details Cephem compounds Cephem compounds

C - Chemistry, Metallurgy

07

D

167/187, 260/104

C07D 501/46 (2006.01) A61K 31/545 (2006.01) C07D 501/38 (2006.01)

Patent

CA 1289555

Cephem Compounds Abstracts of the disclosures Cephem compounds of the formula: Image wherein Q stands for a nitrogen atom or CH, R1 stands for a hydrogen atom or an optionally substituted lower alkyl group, R2 stands for a hydrogen atom or a lower alkyl group, A stands for a sulfur atom or NH, and n denotes an integral number ranging from 2 to 4, or salts thereof, and processes for producing them. The compounds (I) or salts thereof show not only excellent antibacterial activities against a wide range of pathogenic bacteria from gram-positive to gram- negative ones, including a variety of strains isolated clinically but also hydrophilic properties, and therefore they are excellent antibiotic substances having desirable water-solubility when used as injections.

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