Cephem compounds, their production and use

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 501/24 (2006.01) A61K 31/545 (2006.01) A61K 31/695 (2006.01) C07D 501/00 (2006.01) C07D 519/06 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2216433

Cephem compounds of the formula (I) wherein R1 is an optionally protected amino group; R2 is a fluoro-lower alkyl group; and the ring A may have further substituent(s), or their esters or salts, show broad and excellent antibacterial activities and are useful as antibacterial agents.

Composés de cephem représentés par la formule (I) dans laquelle R?1¿ représente un groupe amino éventuellement protégé; R?2¿ représente un groupe fluoro-alkyle inférieur et le noyau A peut posséder un ou plusieurs autres substituants ou leurs esters ou leurs sels. Ces composés possèdent une excellente activité antibactérienne et sont utiles en tant qu'agents antibactériens.

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