Cerebral biopotential analysis system and method

Details Cerebral biopotential analysis system and method Cerebral biopotential analysis system and method

A - Human Necessities

61

B

A61B 5/0476 (2006.01) G06F 17/00 (2006.01)

Patent

CA 2434275

Disclosed is a system and method to obtain 19 unipolar EEG signals from regions of interest on both the left and right hemispheres of a subject's brain. The system uses high-gain, low-noise amplifiers to maximize the dynamic range for low energy wave components of the signals. Band-pass filtering is used to reduce noise and to avoid aliasing. The system applies commonly used digital signal processing (DSP) techniques to digitize, to low-pass filter (50 Hz), and to decimate the signals. Power spectral, bispectral, and higher-order spectral processing is then performed. In a preferred embodiment, the system divides the most recent 63 seconds of digitized EEG data from each lead into 60 4-second intervals, each with 3 seconds of overlap with the previous interval. For a selected set of derived leads, the system produces auto power spectrum, autobispectrum, and auto higher-order spectrum variables, by using either a Fourier Transform based approach or a parametric cubic fitting approach. Any pair of leads can be combined to compute cross power spectrum, cross bispectrum, and cross higher-order spectrum variables.

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