Certain cycloalkyl imidazopyrimidines, a new class of gaba...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01)

Patent

CA 2090853

ABSTRACT This invention encompasses compounds of formula: Image and pharmaceutically acceptable non-toxic salts thereof wherein: n is 0, 1, or 2, X is -N=C-R9 or -NR10-C=T, and R1,R2 R3, W and Y are variables. These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine type drugs, and enhancement of alertness.

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