C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/04 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2294898
Certain diarylimidazoles act as partial agonists or antagonists for NPY receptors, in particular NPY 5 receptors. They are of use, for example in treating loss of appetite. Such compounds bear aryl groups in the 2 position. Many of the compounds are novel.
L'invention concerne certains diarylimidazoles qui agissent comme agonistes partiels ou comme antagonistes de récepteurs de NPY, en particulier de récepteurs de NPY 5. Ces composés sont utiles, par exemple, pour traiter une perte de l'appétit. Ces composés portent des groupes aryle en position 2. Un grand nombre de ces composés sont nouveaux.
Blum Charles A.
Elliot Richard L.
Hammond Marlys
Hutchison Alan
Thurkauf Andrew
Neurogen Corporation
Pfizer Inc.
Smart & Biggar
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