Cervical screening algorithms

G - Physics – 01 – N

Patent

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G01N 33/574 (2006.01)

Patent

CA 2718229

This invention describes new protocols for screening for cervical carcinomas or high-grade premalignant cervical lesions based on combinations of testing for the presence of high-risk HPV, HPV genotyping, marker analysis, and/or cytology. With these protocols the number of women that have to undergo follow-up diagnostic testing and/or clinical examinations will decrease. Further, the number of false positives and false negatives willdecrease.

La présente invention concerne de nouveaux protocoles destinés au dépistage de carcinomes cervicaux ou de lésions cervicales prémalignes peu différenciées, à partir de combinaisons de tests de détection du HPV à haut risque, de génotypage HPV, danalyse des marqueurs, et/ou de cytologie. Ces protocoles permettront de réduire le nombre de femmes devant subir une analyse pour létablissement du diagnostic de suivi et/ou des examens cliniques. En outre, le nombre de faux positifs et de faux négatifs diminuera également.

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