Cetylpyridinium chloride as an antimicrobial agent in...

Details Cetylpyridinium chloride as an antimicrobial agent in... Cetylpyridinium chloride as an antimicrobial agent in...

C - Chemistry, Metallurgy

11

D

C11D 3/00 (2006.01) A61L 12/14 (2006.01) C11D 1/62 (2006.01) C11D 1/835 (2006.01)

Patent

CA 2562546

A multi-purpose contact lens care solution having high antimicrobial activity comprising, in an aqueous liquid medium, cetylpyridinium chloride and a non- ionic surfactant. In one embodiment of the invention, the non-ionic surfactant is a poly(oxypropylene)-poly(oxyethylene) block copolymer. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.

L'invention concerne une solution de soins multifonctionnelle pour lentilles de contact, présentant une activité antimicrobienne élevée, et comprenant, dans une substance liquide aqueuse, du chlorure de cétylpyridinium et un tensioactif non ionique. Dans un mode de réalisation de l'invention, le tensioactif non ionique se présente sous la forme d'un copolymère bloc poly(oxypropylène)-poly(oxyéthylène). Ladite solution peut éventuellement aussi comporter des composants antimicrobiens supplémentaires, un composant tampon, un composant inducteur de viscosité, un tensioactif, de la taurine, du propylèneglycol, et/ou un composant de tonicité. La solution selon l'invention empêche par ailleurs toute modification de l'intégrité de la membrane tissulaire de l'oeil, lors du port de lentilles de contact.

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