Cgi-69 compositions and methods of use

Details Cgi-69 compositions and methods of use Cgi-69 compositions and methods of use

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61P 3/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2414065

An isolated polypeptide comprising an amino acid sequence having at least 80 % sequence identity to the sequence SEQ ID NO:1, polynucleotides encoding these peptides, and antibodies to the polypeptides are useful in treating metabolic disorders or disorders associated with changes in adipose tissue physiological function or mass.

L'invention concerne un polypeptide isolé comprenant une séquence aminoacide présentant au moins 80 % de séquence identique à la séquence SEQ ID NO:1, des polynucléotides codant ces peptides. Des anticorps de ces polypeptides servent à traiter des troubles métaboliques ou des troubles associés à des modifications dans la fonction ou la masse physiologique de tissu adipeux.

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