Cgrp and homolog

Details Cgrp and homolog Cgrp and homolog

C - Chemistry, Metallurgy

07

K

530/7.36

C07K 14/575 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1247603

CGRP AND HOMOLOG ABSTRACT OF THE DISCLOSURE A process for making CGRP (calcitonin-gene- related peptide) having the formula: Image or a related peptide having the residue Lys instead of Glu in the 35-position. CGRP or this homolog or pharmaceutically acceptable salts thereof, dispersed in a pharmaceutically acceptable liquid or solid carrier, can be administered to mammals, including humans, to influence memory, mood and pain appreciation and to achieve a substantial lowering of blood pressure or gastric acid secretion over an extended period of time. They also may be administered to affect ingestion behavior, taste and sensory perception.

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