C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/506 (2006.01) A61P 29/00 (2006.01) C07D 471/10 (2006.01) C07D 498/10 (2006.01) C07D 498/20 (2006.01)
Patent
CA 2702503
The present invention relates to novel CGRP antagonists of the general formula (I) in which U, V, X, Y, R1, R2, and R3 are defined as described below, the tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures, and salts thereof, and the hydrates of the salts, particularly the physiologically compatible salts thereof having inorganic or organic acids or bases, pharmaceuticals comprising said compounds, the use thereof, and method for the production thereof.
L'invention concerne de nouveaux antagonistes du CGRP de formule générale (I), dans laquelle U, V, X, Y, R1, R2 et R3 sont tels que définis dans la description, leurs tautomères, leurs isomères, leurs diastéréoisomères, leurs énantiomères, leurs hydrates, leurs mélanges et leurs sels ainsi que les hydrates des sels, notamment leurs sels physiologiquement compatibles avec des acides ou des bases inorganiques ou organiques. L'invention concerne également des médicaments contenant ces composés, leur utilisation et des procédés pour leur fabrication.
Dahmann Georg
Doods Henri
Gottschling Dirk
Heimann Annekatrin
Mueller Stephan Georg
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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