Cgrp antagonists

Details Cgrp antagonists Cgrp antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61K 31/551 (2006.01) A61P 29/00 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2702563

The present invention relates to new CGRP antagonists of the general formula (I), where U, V, X, Y, R1, R2 and R3 are defined as described below, the tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures, and salts thereof, and the hydrates of said salts, particularly the physiologically compatible salts thereof having inorganic or organic acids or bases, pharmaceuticals comprising said compounds, the use thereof, and method for the production thereof.

L'invention concerne de nouveaux antagonistes du CGRP de formule générale (I), où U, V, X, Y, R1, R2 et R3 sont définis comme mentionné dans la description, leurs tautomères, leurs isomères, leurs diastéréoisomères, leurs énantiomères, leurs hydrates, leurs mélanges et leurs sels ainsi que les hydrates des sels, notamment leurs sels physiologiquement compatibles avec des acides ou des bases inorganiques ou organiques. L'invention concerne également des médicaments contenant ces composés, leur utilisation et des procédés pour leur fabrication.

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