C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/55 (2006.01) A61P 25/06 (2006.01)
Patent
CA 2582593
The present invention is directed to compounds of Formula I: Formula I: I and Formula II: (where variables R1, R2, R3, R4, A, B, J, Q, T, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
L'invention porte sur des composés représentés par la Formule I et la Formule II (dans lesquelles les variables R1, R2, R3, R4, A, B, J, Q, T, V, W, X et Y sont telles que définies ci-après), utiles en tant qu'antagonistes des récepteurs de CGRP et utiles dans le traitement ou la prévention de maladies dans lesquelles CGRP est impliqué, par exemple le mal de tête, la migraine, et l'algie vasculaire de la face. Cette invention concerne aussi des compositions pharmaceutiques contenant ces composés ainsi que l'utilisation de ces composés et compositions dans la prévention ou le traitement des maladies dans lesquelles CGRP est impliqué.
Burgey Christopher S.
Deng James Z.
Potteiger Craig
Williams Theresa M.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Cgrp receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cgrp receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cgrp receptor antagonists will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1356368