Chain-shortened polynucleotide and method for preparation...

Details Chain-shortened polynucleotide and method for preparation... Chain-shortened polynucleotide and method for preparation...

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A61K 9/127 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61P 37/04 (2006.01) A61P 43/00 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2359674

Shortened-chain polynucleotides useful as drugs and medicinal compositions containing the same. Specifically, shortened-chain polynucleotides or salts thereof, characterized by the content of 2'-5' phosphoric diester linkage of 3 % or below based on all the phosphoric diester linkages; and medicinal compositions containing both.

Cette invention se rapporte à des polynucléotides à chaîne raccourcie utiles comme médicaments et à des compositions médicinales contenant ces composés. Cette invention se rapporte plus spécifiquement à des polynucléotides à chaîne raccourcie ou à des sels de ceux-ci qui se caractérisent par une teneur en liaison diester 2'-5'-phosphorique de 3 % au maximum, calculée sur la base de la totalité des liaisons diester phosphorique, ainsi qu'à des compositions médicinales contenant les uns et les autres.

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