C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/18 (2006.01) A61K 31/37 (2006.01) A61P 35/00 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2382112
Disclosed are novel chalcone derivatives having Formula (I). The compounds possess antiproliferative activity, and are useful for the manufacture of a medicament for the treatment or prevention of neoplasms, particularly those located in the uterus, ovary or breast. The compounds of the invention may also be useful in the manufacture of a medicament for the treatment or prevention of menopausal disorders and osteoporosis.
L'invention concerne des dérivés de chacone représentés par la formule (I). Ces composés présentent une activité antiproliférative et sont utiles dans la fabrication d'un médicament servant à traiter ou prévenir les néoplasmes, notamment ceux situés dans l'utérus, les ovaires ou les seins. Ces composés peuvent également être utiles dans la fabrication d'un médicament servant à traiter ou prévenir les troubles de la ménopause et l'ostéoporose.
Bombardelli Ezio
Valenti Piero
Goudreau Gage Dubuc
Indena S.p.a.
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