Chalcone derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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260/476.5, 260/5

C07C 59/90 (2006.01) C07C 45/51 (2006.01) C07C 45/74 (2006.01) C07C 49/84 (2006.01) C07C 69/712 (2006.01) C07C 69/738 (2006.01)

Patent

CA 2022812

ABSTRACT Chalcone derivatives represented by the formula Image wherein R1 is a straight chain, branched chain or cyclic alkyl group having 4 to 15 carbon atoms or an alkenyl group having 3 to 15 carbon atoms, and occurs at the 2- or 4-position, R2 is a hydrogen atom, a straight or branched chain alkyl group having 1 to 3 carbon atoms, and X is a straight or branched chain alkylene group having 1 to 3 carbon atoms, are disclosed. These compounds have anti-ulcer effect, gastric mucosal protection effect and antisecretory effect.

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