Chaotropic method for evaluating nucleic acids in a...

C - Chemistry – Metallurgy – 12 – Q

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150/8.5

C12Q 1/68 (2006.01) C12N 15/00 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 1301606

ABSTRACT OF THE DISCLOSURE The present invention is directed to the discovery that nucleic acid components of a biological sample may be detected and/or quantified utilizing a process wherein the biological sample is first solubilized with a chaotropic salt solution and this solution, containing dissolved nucleic acid, evaluated directly for nucleic acids by molecular hybridization utilizing a labeled probe. The labeled probe may be in immobilized form or may be in solution. A8.1.TXT

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