C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/32 (2006.01) C07K 14/47 (2006.01) C12N 5/18 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2118585
2118585 9401467 PCTABS00030 This invention provides a family of monoclonal antibodies specific for epitopes of p110RB protein present in the nucleus. These antibodies have superior properties that prove useful for the detection of p110RB or its complexes with other cellular regulatory proteins in cells and in cell lysates. This invention also provides hybridoma cell lines that produce such monoclonal antibodies and methods of using these antibodies diagnostically, prognostically and therapeutically. Further, the invention provides a method for isolating proteins associated with p110RB proteins.
Shepard H. Michael
Wen Shu F.
Canji Inc.
Gowling Lafleur Henderson Llp
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