Characterization of c19orf10, a novel synovial protein

Details Characterization of c19orf10, a novel synovial protein Characterization of c19orf10, a novel synovial protein

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61P 19/02 (2006.01) C07K 16/18 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/483 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2589295

Immunofluorescence analysis of cultured cells suggests that the c19orf10 product is localized to the ER/golgi apparatus. The synovial tissue distribution is unique, with staining of both the synovial membrane and the perivascular regions. In some cases there also appears to be an inverse relationship between synovial hyperplasia and c19orf10 expression, raising the possibility that c19orf10 production may be lost during hyperplasia.

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