Characterization of molecules

G - Physics – 01 – N

Patent

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Details

G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/537 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2466663

The invention involves obtaining signatures of species (including chemical, biological, or biochemical molecules) and/or signatures of interactions between species and using them to characterize species, characterize interactions, and/or identify species that could be useful in a variety of settings. Signatures can be obtained using aqueous multi-phase partitioning and can be used to predict molecular interactions for applications such as drug discovery. A plurality of aqueous multi-phase partitioning arrangements can define an overall system providing an information-intensive signature, maximizing precision and sensitivity.

L'invention concerne l'obtention de signatures d'espèces (notamment de molécules chimiques, biologiques, ou biochimiques) et/ou de signatures d'interactions entre espèces et leur utilisation dans la caractérisation d'espèces, la caractérisation d'interactions, et/ou l'identification d'espèces pouvant éventuellement être utiles dans divers paramètres. Ces signatures peuvent s'obtenir au moyen d'une séparation multi-phase aqueuse et peuvent être utilisées pour prédire des interactions moléculaires destinées à des applications telles que le développement de médicaments. Une pluralité d'agencements de séparation multi-phase aqueuse peuvent définir un système global procurant une signature à forte composante d'information, en maximisant la précision et la sensibilité.

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