C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) C07K 14/395 (2006.01) C07K 14/47 (2006.01) C12N 15/31 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2378512
Yeast genes which are differentially expressed during the cell cycle are described. They can be used to study, affect, and monitor the cell cycle of a eukaryotic cell. They can be used to obtain human homologs involved in cell cycle regulation. They can be used to identify antifungal agents and other classes of drugs. They can be formed into arrays on solid supports for interrogation of a cell's transcriptome under various conditions.
Cette invention concerne des gènes de levure exprimés de manière différentielle au cours du cycle cellulaire. On peut les utiliser pour étudier, modifier ou surveiller le cycle cellulaire d'une cellule eucaryote, pour obtenir des homologues humains intervenant dans la régulation du cycle cellulaire, et pour identifier des agents antifongiques ou autres classes de médicaments. On peut les constituer en réseaux sur des supports solides aux fins d'analyse d'un transcriptome de cellule dans diverses conditions.
Kinzler Kenneth
Velculescu Victor
Vogelstein Bert
Sim & Mcburney
The Johns Hopkins University
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