C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) C07K 14/395 (2006.01) C12N 15/31 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2278645
Yeast genes which are differentially expressed during the cell cycle are described. They can be used to study, affect, and monitor the cell cycle of a eukaryotic cell. They can be used to obtain human homologs involved in cell cycle regulation. They can be used to identify antifungal agents. They can be formed into arrays on solid supports for interrogation of a cell's transcriptome under various conditions.
Cette invention concerne des gènes de levure qui sont exprimés de manière différentielle au cours du cycle cellulaire. On peut les utiliser pour étudier, modifier et surveiller le cycle cellulaire d'une cellule eucaryote; pour obtenir des homologues humains impliqués dans la régulation du cycle cellulaire, et pour identifier des agents antifongiques. On peut les former sous forme de réseaux sur des supports solides pour étudier un transcriptome de cellule dans diverses conditions.
Kinzler Kenneth W.
Velculescu Victor E.
Vogelstein Bert
Finlayson & Singlehurst
The Johns Hopkins University School Of Medicine
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